Eduardo Nicol: Totalitarianism and the Regime of Force Majeure in Life. The World against the Total Violence

Se propone una mirada filosófica amplia sobre la situación de la violencia en el siglo XX y XXI, y se brinda un concepto de totalitarismo que, finalmente, opera temáticamente en la obra del filósofo exiliado Eduardo Nicol. La finalidad del escrito es poner de manifiesto el diagnóstico de la obra nicoliana sobre un periodo y la comprensión de una época que, como sostenemos, afecta directamente a la actualidad, en la que el totalitarismo no se restringe a una esfera de lo político o a una arqueología de teorías políticas del siglo pasado; antes bien, el trazado del totalitarismo político es el de una emergente manera de ser humana, total y totalizante, en donde se dan cita formas sistemáticas de regulación y de control en el ejercicio del poder, propias de un ser sin verdad que ni da ni pide razones; propias de una idea de hombre distante del humanismo, plegada en la indiferencia, en una nueva barbarie en donde predomina la masificación social, la ideología, el movimiento y la propaganda espectacularThis article takes a critical look at the situation of violence in the Twentieth and Twenty-first century, provides, from the philosophy of exile in the work of Eduardo Nicol, a concept of totalitarianism that operates thematically in the work of the philosopher in a text published in 1942 (almost unknown until now) and throughout his work. The purpose of this written contribution is to demonstrate the diagnosis of nicoliana work over a period and understanding of an age that directly affects our present, in which totalitarianism is not restricted to a sphere of politics or an archeology political theories of the last century; rather, the trajectory of political totalitarianism is the outline of a way of being human, the total and totalizing, one without truth being, that neither gives nor asks for reasons, an idea man folded into indifference, a new barbarism enlightened in wich predominant social massification, ideology, movement and spectacular propagand

Eduardo Nicol: el totalitarismo y el régimen de fuerza mayor en la vida. El mundo ante la violencia total / Eduardo Nicol: Totalitarianism and the Regime of Force Majeure in Life. The World against the Total Violence

Se propone una mirada filosófica amplia sobre la situación de la violencia en el siglo XX y XXI, y se brinda un concepto de totalitarismo que, finalmente, opera temáticamente en la obra del filósofo exiliado Eduardo Nicol. La finalidad del escrito es poner de manifiesto el diagnóstico de la obra nicoliana sobre un periodo y la comprensión de una época que, como sostenemos, afecta directamente a la actualidad, en la que el totalitarismo no se restringe a una esfera de lo político o a una arqueología de teorías políticas del siglo pasado; antes bien, el trazado del totalitarismo político es el de una emergente manera de ser humana, total y totalizante, en donde se dan cita formas sistemáticas de regulación y de control en el ejercicio del poder, propias de un ser sin verdad que ni da ni pide razones; propias de una idea de hombre distante del humanismo, plegada en la indiferencia, en una nueva barbarie en donde predomina la masificación social, la ideología, el movimiento y la propaganda espectacular.Palabras Clave: Eduardo Nicol, totalitarismo, autoritarismo, Hannah Arentd, violencia, exilio republicano español.Abstract:This article takes a critical look at the situation of violence in the Twentieth and Twenty-first century, provides, from the philosophy of exile in the work of Eduardo Nicol, a concept of totalitarianism that operates thematically in the work of the philosopher in a text published in 1942 (almost unknown until now) and throughout his work. The purpose of this written contribution is to demonstrate the diagnosis of nicoliana work over a period and understanding of an age that directly affects our present, in which totalitarianism is not restricted to a sphere of politics or an archeology political theories of the last century; rather, the trajectory of political totalitarianism is the outline of a way of being human, the total and totalizing, one without truth being, that neither gives nor asks for reasons, an idea man folded into indifference, a new barbarism enlightened in wich predominant social massification, ideology, movement and spectacular propaganda.Keywords: Eduardo Nicol, Totalitarism, Autoritarism, Violence, Hannah Arendt, Spanish Republican exile.</p

Removal of Te and Se anions in alkaline media in presence of cyanide by quaternary ammonium salts

Precious metals are currently associated with selenium (naumannite, Ag2Se) and tellurium (calaverite, AuTe2; sylvanite, (Au,Ag)2Te4) to form species refractory to cyanidation. The aim of this preliminary work was to study the use of the solvent extraction technique to recover tellurium and selenium ions from a synthetic solution similar to the cyanidation effluents to recycle the free cyanide back to the process. For the extraction of the Se and Te anions, the use of quaternary amines as extractants was evaluated (tallow trimethyl ammonium chloride, Quartamin TPR; hexadecyl trimethyl ammonium chloride, Amine F; and trioctyl methyl ammonium chloride, Aliquat 336) employing nonylphenol as a modifier in the organic phase (iso-octane). The results obtained showed that the extraction was strongly affected by the pH and that it was possible to recover up to 83% of Se and 10% of Te with Quartamin TPR from two synthetic solutions containing 23 mg/L of Te and 20 mg/L of Se with a molar cyanide:metal ratio of 1:4 at pH 11, a ratio of aqueous/organic (A/O) = 1 (V/V) and an extractant concentration of 0.022 mol/L. A maximum distribution coefficient (D) of 4.97 was obtained at pH 11. The McCabe-Thiele diagram indicates that two theoretical extraction stages are necessary to obtain a good extraction of Se complexes using Quartamin TPR.Precious metals are currently associated with selenium (naumannite, Ag2Se) and tellurium (calaverite, AuTe2; sylvanite, (Au,Ag)2Te4) to form species refractory to cyanidation. The aim of this preliminary work was to study the use of the solvent extraction technique to recover tellurium and selenium ions from a synthetic solution similar to the cyanidation effluents to recycle the free cyanide back to the process. For the extraction of the Se and Te anions, the use of quaternary amines as extractants was evaluated (tallow trimethyl ammonium chloride, Quartamin TPR; hexadecyl trimethyl ammonium chloride, Amine F; and trioctyl methyl ammonium chloride, Aliquat 336) employing nonylphenol as a modifier in the organic phase (iso-octane). The results obtained showed that the extraction was strongly affected by the pH and that it was possible to recover up to 83% of Se and 10% of Te with Quartamin TPR from two synthetic solutions containing 23 mg/L of Te and 20 mg/L of Se with a molar cyanide:metal ratio of 1:4 at pH 11, a ratio of aqueous/organic (A/O) = 1 (V/V) and an extractant concentration of 0.022 mol/L. A maximum distribution coefficient (D) of 4.97 was obtained at pH 11. The McCabe-Thiele diagram indicates that two theoretical extraction stages are necessary to obtain a good extraction of Se complexes using Quartamin TPR

Métricas de Registro de Imágenes y Predicción de Dolor de Rodilla por Osteoartritis Crónica: Datos de la Osteoarthritis Initiative

Osteoarthritis (OA) is the most common type of arthritis, is a growing disease in the industrialized world. OA is an incapacitate disease that affects more than 1 in 10 adults over 60 years old. X-ray medical imaging is a primary diagnose technique used on staging OA that the expert reads and quantify the stage of the disease. Some Computer-Aided Diagnosis (CADx) efforts to automate the OA detection have been made to aid the radiologist in the detection and control, nevertheless, the pain inherits to the disease progression is left behind. In this research, it’s proposed a CADx system that quantify the bilateral similarity of the patient’s knees to correlate the degree of asymmetry with the pain development. Firstly, the knee images were aligned using a B-spline image registration algorithm, then, a set of similarity measures were quantified, lastly, using this measures it’s proposed a multivariate model to predict the pain development up to 48 months. The methodology was validated on a cohort of 131 patients from the Osteoarthritis Initiative (OAI) database. Results suggest that mutual information can be associated with K&L OAI scores, and Multivariate models predicted knee chronic pain with: AUC 0.756, 0.704, 0.713 at baseline, one year, and two years’ follow-up.Osteoarthritis (OA) is the most common type of arthritis, is a growing disease in the industrialized world. OA is an incapacitate disease that affects more than 1 in 10 adults over 60 years old. X-ray medical imaging is a primary diagnose technique used on staging OA that the expert reads and quantify the stage of the disease. Some Computer-Aided Diagnosis (CADx) efforts to automate the OA detection have been made to aid the radiologist in the detection and control, nevertheless, the pain inherits to the disease progression is left behind. In this research, it’s proposed a CADx system that quantify the bilateral similarity of the patient’s knees to correlate the degree of asymmetry with the pain development. Firstly, the knee images were aligned using a B-spline image registration algorithm, then, a set of similarity measures were quantified, lastly, using this measures it’s proposed a multivariate model to predict the pain development up to 48 months. The methodology was validated on a cohort of 131 patients from the Osteoarthritis Initiative (OAI) database. Results suggest that mutual information can be associated with K&L OAI scores, and Multivariate models predicted knee chronic pain with: AUC 0.756, 0.704, 0.713 at baseline, one year, and two years’ follow-up

Speed Bump Detection Using Accelerometric Features: A Genetic Algorithm Approach

AmongthecurrentchallengesoftheSmartCity,trafficmanagementandmaintenanceareof utmostimportance. Roadsurfacemonitoringiscurrentlyperformedbyhumans,buttheroadsurface condition is one of the main indicators of road quality, and it may drastically affect fuel consumption and the safety of both drivers and pedestrians. Abnormalities in the road, such as manholes and potholes, can cause accidents when not identified by the drivers. Furthermore, human-induced abnormalities, such as speed bumps, could also cause accidents. In addition, while said obstacles ought to be signalized according to specific road regulation, they are not always correctly labeled. Therefore, we developed a novel method for the detection of road abnormalities (i.e., speed bumps). This method makes use of a gyro, an accelerometer, and a GPS sensor mounted in a car. After having the vehicle cruise through several streets, data is retrieved from the sensors. Then, using a cross-validation strategy, a genetic algorithm is used to find a logistic model that accurately detects road abnormalities. The proposed model had an accuracy of 0.9714 in a blind evaluation, with a false positive rate smaller than 0.018, and an area under the receiver operating characteristic curve of 0.9784. This methodology has the potential to detect speed bumps in quasi real-time conditions, and can be used to construct a real-time surface monitoring system.AmongthecurrentchallengesoftheSmartCity,trafficmanagementandmaintenanceareof utmostimportance. Roadsurfacemonitoringiscurrentlyperformedbyhumans,buttheroadsurface condition is one of the main indicators of road quality, and it may drastically affect fuel consumption and the safety of both drivers and pedestrians. Abnormalities in the road, such as manholes and potholes, can cause accidents when not identified by the drivers. Furthermore, human-induced abnormalities, such as speed bumps, could also cause accidents. In addition, while said obstacles ought to be signalized according to specific road regulation, they are not always correctly labeled. Therefore, we developed a novel method for the detection of road abnormalities (i.e., speed bumps). This method makes use of a gyro, an accelerometer, and a GPS sensor mounted in a car. After having the vehicle cruise through several streets, data is retrieved from the sensors. Then, using a cross-validation strategy, a genetic algorithm is used to find a logistic model that accurately detects road abnormalities. The proposed model had an accuracy of 0.9714 in a blind evaluation, with a false positive rate smaller than 0.018, and an area under the receiver operating characteristic curve of 0.9784. This methodology has the potential to detect speed bumps in quasi real-time conditions, and can be used to construct a real-time surface monitoring system

A Case–Control Study of Socio-Economic and Nutritional Characteristics as Determinants of Dental Caries in Different Age Groups, Considered as Public Health Problem: Data from NHANES 2013–2014

One of the principal conditions that affects oral health worldwide is dental caries, occurring in about 90% of the global population. This pathology has been considered a challenge because of its high prevalence, besides being a chronic but preventable disease which can be caused by a series of different demographic, dietary, among others. Based on this problem, in this research a demographic and dietary features analysis is performed for the classification of subjects according to their oral health status based on caries, according to the age group where the population belongs, using as feature selector a technique based on fast backward selection (FBS) approach for the development of three predictive models, one for each age range (group 1: 10–19; group 2: 20–59; group 3: 60 or more years old). As validation, a net reclassification improvement (NRI), AUC, ROC, and OR values are used to evaluate their classification accuracy. We analyzed 189 demographic and dietary features from National Health and Nutrition Examination Survey (NHANES) 2013–2014. Each model obtained statistically significant results for most features and narrow OR confidence intervals. Age group 2 obtained a mean NRI = −0.080 and AUC = 0.933; age group 3 obtained a mean NRI = −0.024 and AUC = 0.787; and age group 4 obtained a mean NRI = −0.129 and AUC = 0.735. Based on these results, it is concluded that these specific demographic and dietary features are significant determinants for estimating the oral health status in patients based on their likelihood of developing caries, and the age group could imply different risk factors for subject

A Case–Control Study of Socio-Economic and Nutritional Characteristics as Determinants of Dental Caries in Different Age Groups, Considered as Public Health Problem: Data from NHANES 2013–2014

One of the principal conditions that affects oral health worldwide is dental caries, occurring in about 90% of the global population. This pathology has been considered a challenge because of its high prevalence, besides being a chronic but preventable disease which can be caused by a series of different demographic, dietary, among others. Based on this problem, in this research a demographic and dietary features analysis is performed for the classification of subjects according to their oral health status based on caries, according to the age group where the population belongs, using as feature selector a technique based on fast backward selection (FBS) approach for the development of three predictive models, one for each age range (group 1: 10–19; group 2: 20–59; group 3: 60 or more years old). As validation, a net reclassification improvement (NRI), AUC, ROC, and OR values are used to evaluate their classification accuracy. We analyzed 189 demographic and dietary features from National Health and Nutrition Examination Survey (NHANES) 2013–2014. Each model obtained statistically significant results for most features and narrow OR confidence intervals. Age group 2 obtained a mean NRI = −0.080 and AUC = 0.933; age group 3 obtained a mean NRI = −0.024 and AUC = 0.787; and age group 4 obtained a mean NRI = −0.129 and AUC = 0.735. Based on these results, it is concluded that these specific demographic and dietary features are significant determinants for estimating the oral health status in patients based on their likelihood of developing caries, and the age group could imply different risk factors for subject

Contralateral asymmetry for breast cancer detection : A CADx approach

Early detection is fundamental for the effective treatment of breast cancer and the screening mammography is the most common tool used by the medical community to detect early breast cancer development. Screening mammograms include images of both breasts using two standard views, and the contralateral asymmetry per view is a key feature in detecting breast cancer. we propose a methodology to incorporate said asymmetry information into a computer-aided diagnosis system that can accurately discern between healthy subjects and subjects at risk of having breast cancer. Furthermore, we generate features that measure not only a view-wise asymmetry, but a subject-wise one. Briefly, the methodology co-registers the left and right mammograms, extracts image characteristics, fuses them into subjectwise features, and classifies subjects. In this study, 152 subjects from two independent databases, one with analog- and one with digital mammograms, were used to validate the methodology. Areas under the receiver operating characteristic curve of 0.738 and 0.767, and diagnostic odds ratios of 23.10 and 9.00 were achieved, respectively. In addition, the proposed method has the potential to rank subjects by their probability of having breas

Clinical practice guideline for surgical antimicrobial prophylaxis

La infección del sitio quirúrgico (ISQ) es una de las principales causas de infecciones asociadas a la atención en salud (IAAS), con un impacto significativo en la mortalidad y morbilidad del paciente quirúrgico, así como en los costos asociados a la atención en salud. El adecuado uso de la profilaxis quirúrgica antimicrobiana es un aspecto fundamental en la reducción del riesgo de ISQ, dado que su utilización inapropiada o indiscriminada puede representar un riesgo para los pacientes y contribuir al desarrollo de resistencia a los antimicrobianos, por lo que resulta de importancia generar directrices que permitan orientar el uso adecuado de antimicrobianos en la profilaxis del paciente quirúrgico, con el objetivo de obtener mejores desenlaces clínicos y propender por un uso racional de antibióticos. La presente guía contiene recomendaciones para profilaxis antibiótica de pacientes sometidos a procedimiento quirúrgico, basadas en la evidencia, realizadas mediante el proceso de adaptación de guías de práctica clínica para el contexto colombiano.Q4Pacientes sometidos a Profilaxis quirúrgica antimicrobianaSurgical site infection (SSI) is one of the main causes of healthcare associated infections (HAI), with a significant impact on the mortality and morbidity of the surgi-cal patient, as well as on the costs associated with health care. The adequate use of surgical antimicrobial prophylaxis being a fundamental aspect in reducing the risk of SSI, taking into account that the inappropriate or indiscriminate use of antibiotics in surgical prophylaxis may represent a risk for patients and contribute to the development of antimicrobial resistance, so it is important to generate guidelines that guide the appropriate antimicrobial prophylaxis in the surgical patient, with the aim of obtaining better clinical outcomes and promoting a rational use of antibiotics. This guide contains recommendations for antibiotic prophylaxis in patients undergoing a surgical procedure, based on evidence, carried out through the process of adapting clinical practice guidelines for the Colombian context.https://orcid.org/0000-0002-5392-7083https://orcid.org/0000-0003-2568-4667Revista Nacional - IndexadaCN

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation